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Research team-university develops a compound to melt gallstones

29.03.2021

The Korea Chemical Technology Research Institute (KRICT) and the Catholic University School of Medicine have developed a new compound that dissolves gallstones. gallstones with low side effects and high efficiency and transferred the technology to Surginex.

The joint research team demonstrated the efficacy of the new compound in dissolving gallstones from hamster models, which showed fewer side effects and favorable fusion effects on gallstones, KRICT said Monday.

The compound also melts cholesterol polyps, which has a wide range of uses, the state institute said.

The Korea Chemical Technology Research Institute and the Catholic University School of Medicine have developed a new compound for dissolving gallstones with low side effects and high efficiency. (KRICT) "src =" https://cdn.koreabiomed.com/news/photo/202103/10801_11000_420.jpg "/> <figcaption> The Korea Chemical Technology Research Institute and the Catholic University School of Medicine have developed a new compound for dissolving gallstones with low side effects and high efficiency. (KRICT) </figcaption></figure></p></div><p> Cholelithiasis is a disease characterized by the hardening of part of the bile, a digestive fluid, in the gallbladder. A high percentage of cholesterol often causes bile condition due to consumption of fatty foods and lack of exercise. An estimated 10 to 20 percent of Westerners and 5 to 10 percent of Koreans are patients with gallbladder disease. Some 210,000 Koreans visited hospitals due to cholelithiasis in 2019.</p><p> Approximately 80 percent of patients with cholelithiasis are asymptomatic. However, if the gallstone becomes enlarged, it creates immense pain and inflammation. To prevent such pain, people are advised to track gallstone size or receive treatment, KRICT said.</p><p> The previous treatment was resection of the gallbladder, but its removal causes diarrhea and abdominal pain. However, the new gallstone compound dissolves only the gallstone without gallbladder resection.</p><p> “There is a steady increase in the number of cholelithiasis patients in Korea. The new compound is likely to improve patients' quality of life as it does not interfere with gallbladder function and only removes gallstones, said KRICT Director Lee Mi-hye.</p><p> The research-university-industry team will continue their joint project to commercialize the gallstone-dissolving compound as soon as possible, he added.</p></p></div> </pre><p> <a href= Source link

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